Miles leaves the block after climbing up through the cell area, eventually reaching the Sewer through a hole in the shower room. Walker will follow soon after, forcing Miles to evade him and find an alternate path to the showers.

While attempting to run past the fire, an explosion occurs, blasting Miles into the lower floor of the Prison Block and on to a pile of body parts. Chris will try to follow by bursting through a door, and will subsequently give chase to Miles. An air vent then opens, allowing Miles to escape through the air duct. After reaching the security control for the fourth airlock, Chris Walker will appear from the other side and smash his way through reinforced glass, causing the airlock to malfunction and burst into flame. This forces him to use the smashed window to evade them.

After passing through a destroyed airlock, Miles will find a keycard lying on the floor, which he can use to access the showers however, he will be ambushed by the twins, who manage to trap him in a narrow corridor. As soon as he emerges, however, the twins will vanish. Once he goes back, Miles will encounter the twins - again, behind iron bars - and will have to traverse a window ledge to get to the other side. A control room at the end of the hallway is guarded by an armed Variant the player must outmaneuver him and activate the airlock. After dropping down the hole, the player will be required to find a switch for an airlock. Upon reaching the upper level (Block A), Miles encounters a Variant, and the bloody message 'Down the drain' on the walls is repeated, this time with an arrow pointing towards a hole in the floor.

He traverses a ledge and proceeds through the decontamination chamber, following the blood towards the exit. Miles then proceeds to the lower level of the Prison Block and passes through a crack in the wall in one of the cells to reach the other side of the prison's balcony. They discuss the idea of killing Miles and taking his tongue and liver, but decide not to do so yet, believing it to be impolite towards Father Martin, who told them not to touch Miles. Miles leaves the cell and encounters The Twins, mysterious Variants, standing on the other side of the prison balcony behind iron bars. When he approaches the door, one of the patients unlocks the door for him and quickly leaves.

After being sedated and dragged by Father Martin, Miles wakes up in a locked padded cell, with the phrase 'Rest in Peace' written in blood on the wall.

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